The intracellular targets of motion of metronidazole on anaerobes are mainly unidentified. The 5-nitro group of metronidazole is minimized by metabolically Lively anaerobes, and scientific tests have shown the decreased type of the drug interacts with bacterial DNA.
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There have been no working experience up to now with using METROGEL® (metronidazole topical gel) Topical Gel in pregnant people. Metronidazole crosses the placental barrier and enters the fetal circulation rapidly.
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Utilization of cimetidine with oral metronidazole could extend the fifty percent-daily life and decrease plasma clearance of metronidazole.
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The next adverse reactions and altered laboratory tests are actually described With all the oral jnetoto or parenteral usage of metronidazole:
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